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DENALI THERAPEUTICS INC.

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Registration No.
3770646
Incorporation Date
2015-03-25
Company Type
Not disclosed
Address
United States
Website
www.denalitherapeutics.com/
Source: California Secretary of State — bizfile Online

DENALI THERAPEUTICS INC. is a registered legal entity registered in United States under 3770646, and its current status with California Secretary of State — bizfile Online is active. The company was incorporated on 25 March 2015 and lists its registered address as United States. 5 shareholders are on record for DENALI THERAPEUTICS INC., and since every one of them is a company rather than an individual, this particular filing does not on its own establish an ultimate beneficial owner (UBO) — identifying one would mean tracing the ownership of each shareholding company in turn. This profile is sourced directly from California Secretary of State — bizfile Online and was last updated on 22 September 2026.

Data Provenance
This record is sourced directly from official government registries, including California Secretary of State — bizfile Online.

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Shareholders

5

Shareholders of DENALI THERAPEUTICS INC.

Five shareholders are currently on record for DENALI THERAPEUTICS INC., reflecting the stock ledger maintained under state corporate law (e.g. §219 of the Delaware General Corporation Law) rather than a public filing. The largest of these is BAILLIE GIFFORD & CO, holding 12.3% — the largest recorded stake — followed by VANGUARD INDEX FUNDS-Vanguard Total Stock Market Index Fund at 3.8%; the remaining 3 shareholders shown hold smaller stakes. Because every shareholder shown is a company rather than an individual, the ownership chain continues above this level, and no beneficial owner can be established from this filing alone.

Data availability

The register reports 7 shareholders in total, though only the top 5 by holding are shown in this view.

Shareholder Type Holding Source Document
BAILLIE GIFFORD & CO 12.3% California Secretary of State — bizfile Online
VANGUARD INDEX FUNDS-Vanguard Total Stock Market Index Fund 3.8% California Secretary of State — bizfile Online
iShares Trust-iShares Russell 2000 ETF 3.3% California Secretary of State — bizfile Online
SPDR SERIES TRUST-State Street SPDR S&P Biotech ETF 3.2% California Secretary of State — bizfile Online
T. Rowe Price Health Sciences Fund, Inc. 1.6% California Secretary of State — bizfile Online

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Officers

5

Directors and officers of DENALI THERAPEUTICS INC.

The Chief Executive Officer of DENALI THERAPEUTICS INC. currently on record is Ryan Watts; five officers are currently on record for DENALI THERAPEUTICS INC., filed with California Secretary of State — bizfile Online. Management authority at DENALI THERAPEUTICS INC. sits with these individuals, not with shareholders, who are covered separately and hold ownership rather than control. The source filing doesn't specify representation authority — whether officers can act individually or must sign jointly to bind the company — so that detail isn't available here.

Data availability

The register reports 22 officers in total, including past appointments, though only the 5 most relevant records are shown here.

RW
Ryan Watts ACTIVE

Residence
🇺🇸 United States
Occupation
Chief Executive Officer

DA
Dana Andersen ACTIVE

Appointed
2018-08-01
Residence
🇺🇸 United States
Occupation
Chief Technical And Manufacturing Officer

LH
Laura Hansen ACTIVE

Appointed
2020-09-01
Residence
🇺🇸 United States
Occupation
Vice President Of Investor Relations

LH
Laura Hansen Ph.d. ACTIVE

Residence
🇺🇸 United States
Occupation
Vice President Of Investor Relations

CW
Chris Walsh J.d. ACTIVE

Residence
🇺🇸 United States
Occupation
General Counsel

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Group Structure

Group structure of DENALI THERAPEUTICS INC.

DENALI THERAPEUTICS INC. has no recorded parent company — it sits at the top of its own group structure, with 3 subsidiaries recorded beneath it across 3 jurisdictions. Each of these downward relationships is derived rather than filed: resolved by matching entities across the registry network, not stated directly in a single document.

  • Smart Recycling Us, LLC (United States)
  • DENALI BBB HOLDING LIMITED (United Kingdom)
  • Denali Therapeutics CH GmbH (Switzerland)

Data availability

Those 3 subsidiaries span United States, United Kingdom, Switzerland jurisdictions, though this list should not be read as complete — subsidiaries only become visible here where shareholder data has actually been filed with a register, so holdings in jurisdictions without that filing simply won't appear.

Ultimate HQ
DENALI THERAPEUTICS INC.
United States
Smart Recycling Us, LLC
United States#0191170986

DENALI BBB HOLDING LIMITED
United KingdomGB 10214672

Denali Therapeutics CH GmbH
SwitzerlandCH CHE-487.887.939

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Frequently Asked Questions

Who owns DENALI THERAPEUTICS INC.?

Five shareholders are currently on record for DENALI THERAPEUTICS INC., reflecting the stock ledger maintained under state corporate law (e.g. §219 of the Delaware General Corporation Law) rather than a public filing. The largest of these is BAILLIE GIFFORD & CO, holding 12.3% — the largest recorded stake — followed by VANGUARD INDEX FUNDS-Vanguard Total Stock Market Index Fund at 3.8%; the remaining 3 shareholders shown hold smaller stakes. Because every shareholder shown is a company rather than an individual, the ownership chain continues above this level, and no beneficial owner can be established from this filing alone.

Who is DENALI THERAPEUTICS INC.'s UBO (Ultimate Beneficial Owner)?

Every shareholder recorded for DENALI THERAPEUTICS INC. is itself a company rather than a natural person, so no Ultimate Beneficial Owner (UBO) is identified at this level; establishing one would require tracing the ownership of each shareholding company in turn.

How many shareholders does DENALI THERAPEUTICS INC. have on record?

5 shareholders are shown on record for DENALI THERAPEUTICS INC.. The register reports 7 in total; only the top 5 by holding are shown here.

What is DENALI THERAPEUTICS INC.'s company registration number?

DENALI THERAPEUTICS INC.'s registration number is 3770646, filed with California Secretary of State — bizfile Online in United States. Its current status on the register is active.

Is DENALI THERAPEUTICS INC. still an active company?

DENALI THERAPEUTICS INC.'s status on California Secretary of State — bizfile Online is listed as active.

When was DENALI THERAPEUTICS INC. incorporated?

DENALI THERAPEUTICS INC. was incorporated on 25 March 2015, according to California Secretary of State — bizfile Online.

What is DENALI THERAPEUTICS INC.'s registered address?

The registered address on file for DENALI THERAPEUTICS INC. is United States.

Who are the officers/directors of DENALI THERAPEUTICS INC.?

The Chief Executive Officer of DENALI THERAPEUTICS INC. currently on record is Ryan Watts; five officers are currently on record for DENALI THERAPEUTICS INC., filed with California Secretary of State — bizfile Online. Management authority at DENALI THERAPEUTICS INC. sits with these individuals, not with shareholders, who are covered separately and hold ownership rather than control.

Does DENALI THERAPEUTICS INC. have a parent company or subsidiaries?

DENALI THERAPEUTICS INC. has no recorded parent company — it sits at the top of its own group structure, with 3 subsidiaries recorded beneath it across 3 jurisdictions. Those 3 subsidiaries span United States, United Kingdom, Switzerland jurisdictions, though this list should not be read as complete — subsidiaries only become visible here where shareholder data has actually been filed with a register, so holdings in jurisdictions without that filing simply won't appear.

Can Zavia monitor changes to DENALI THERAPEUTICS INC.'s ownership over time?

This profile reflects a point-in-time snapshot from California Secretary of State — bizfile Online. Zavia's monitoring API can track changes to DENALI THERAPEUTICS INC.'s registered shareholders, officers, and group structure going forward, flagging updates as they're filed rather than requiring a manual recheck.

Can I access DENALI THERAPEUTICS INC.'s data through an API?

Yes. Zavia's API connects directly to official government ownership registries across 195 countries and territories, including United States, so records like DENALI THERAPEUTICS INC.'s registration, shareholder, UBO, and group-structure data can be queried programmatically instead of viewed one page at a time.

Where does this company information come from, and how current is it?

This record is sourced directly from California Secretary of State — bizfile Online and was last synced on 22 September 2026.

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