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OPKO HEALTH, INC.

Active

in

Registration No.
F07000003863
Incorporation Date
2007-07-31
Company Type
Not disclosed
Address
Miami, United States
Website
opko.com/
Source: Florida Department of State — Sunbiz

OPKO HEALTH, INC. is a registered legal entity registered in United States under F07000003863, and its current status with Florida Department of State — Sunbiz is active. The company was incorporated on 31 July 2007 and lists its registered address as Miami, United States. 5 shareholders are on record for OPKO HEALTH, INC., and since every one of them is a company rather than an individual, this particular filing does not on its own establish an ultimate beneficial owner (UBO) — identifying one would mean tracing the ownership of each shareholding company in turn. This profile is sourced directly from Florida Department of State — Sunbiz and was last updated on 16 September 2026.

Data Provenance
This record is sourced directly from official government registries, including Florida Department of State — Sunbiz.

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Shareholders

5

Shareholders of OPKO HEALTH, INC.

Five shareholders are currently on record for OPKO HEALTH, INC., reflecting the stock ledger maintained under state corporate law (e.g. §219 of the Delaware General Corporation Law) rather than a public filing. The largest of these is iShares Trust-iShares Russell 2000 ETF, holding 5% — the largest recorded stake — followed by iShares Trust-iShares Russell 2000 ETF at 4.8%; the remaining 3 shareholders shown hold smaller stakes. Because every shareholder shown is a company rather than an individual, the ownership chain continues above this level, and no beneficial owner can be established from this filing alone.

Data availability

The register reports 7 shareholders in total, though only the top 5 by holding are shown in this view.

Shareholder Type Holding Source Document
iShares Trust-iShares Russell 2000 ETF 5% Florida Department of State — Sunbiz
iShares Trust-iShares Russell 2000 ETF 4.8% Florida Department of State — Sunbiz
Fidelity Salem Street Trust-Fidelity Small Cap Index Fund 2% Florida Department of State — Sunbiz
iShares Trust-iShares Russell 2000 Value ETF 1.7% Florida Department of State — Sunbiz
iShares Trust-iShares Biotechnology ETF 1.4% Florida Department of State — Sunbiz

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Full cap table, ownership percentages, and ultimate beneficial owners resolved down to the natural person.

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Officers

21

Directors and officers of OPKO HEALTH, INC.

The Chairman & Ceo of OPKO HEALTH, INC. currently on record is Phillip Frost Ph.d.; 21 officers are currently on record for OPKO HEALTH, INC., filed with Florida Department of State — Sunbiz. Management authority at OPKO HEALTH, INC. sits with these individuals, not with shareholders, who are covered separately and hold ownership rather than control. The source filing doesn't specify representation authority — whether officers can act individually or must sign jointly to bind the company — so that detail isn't available here.

PF
Phillip Frost Ph.d. ACTIVE

Residence
🇺🇸 United States
Occupation
Chairman & Ceo

PF
Phillip Frost M.d., Ph.d. ACTIVE

Residence
🇺🇸 United States
Occupation
Chairman & Ceo

FP
FROST PHILLIP ACTIVE

Residence
🇺🇸 United States
Occupation
Ceo

CW
Charles W. Bishop ACTIVE

Residence
🇺🇸 United States
Occupation
Chief Executive Officer Of Opko Renal

CW
Charles W. Bishop Ph.d. ACTIVE

Residence
🇺🇸 United States
Occupation
Chief Executive Officer Of Opko Renal

GJ
Gary J. Nabel M.d., Ph.d. ACTIVE

Residence
🇺🇸 United States
Occupation
Chief Innovation Officer & Director

SD
Steven D. Rubin Esq., J.d. ACTIVE

Residence
🇺🇸 United States
Occupation
Executive Vp Of Administration & Director

HJ
Hsiaotransi JANE ACTIVE

Residence
🇺🇸 United States
Occupation
Vc

AA
Akhtar Ashfaq Facp, Fasn, M.d. ACTIVE

Residence
🇺🇸 United States
Occupation
Senior Vice President Of Clinical Research & Development And Medical Affairs – Opko Renal

LA
LOGAL ADAM ACTIVE

Residence
🇺🇸 United States
Occupation
Cfo

JH
Jane H. Hsiao M.b.a., Ph.d. ACTIVE

Residence
🇺🇸 United States
Occupation
Vice Chairman & Chief Technical Officer

AF
Antonio F. Cruz ACTIVE

Residence
🇺🇸 United States
Occupation
President Of Transition Therapeutics

RS
RUBIN STEPHEN ACTIVE

Residence
🇺🇸 United States
Occupation
Vp

IK
Inman Kate ACTIVE

Residence
🇺🇸 United States
Occupation
Secr

JR
John R. Mascola M.d. ACTIVE

Residence
🇺🇸 United States
Occupation
Chief Scientific Officer Of Modex

AE
Adam E. Logal ACTIVE

Residence
🇺🇸 United States
Occupation
Senior Vp & Cfo

HB
Hans Berner ACTIVE

Residence
🇺🇸 United States
Occupation
President Of Opko Health Iberoamerica

AG
Arie Gutman Ph.d. ACTIVE

Residence
🇺🇸 United States
Occupation
President Of Api

CS
CORPORATION SERVICE COMPANY ACTIVE ENTITY

Residence
🇺🇸 United States
Occupation
Agent

EA
Elias Adam Zerhouni M.d. ACTIVE

Residence
🇺🇸 United States
Occupation
President & Vice Chairman

GA
Giovanni Abbadessa M.d., Ph.d. ACTIVE

Residence
🇺🇸 United States
Occupation
Chief Medical Officer

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Group Structure

Group structure of OPKO HEALTH, INC.

OPKO HEALTH, INC. has no recorded parent company — it sits at the top of its own group structure, with 12 subsidiaries recorded beneath it across 4 jurisdictions. Each of these downward relationships is derived rather than filed: resolved by matching entities across the registry network, not stated directly in a single document.

  • Opko Diagnostics, LLC (United States)
  • Opko Pharmaceuticals, LLC (United States)
  • Pharmacos Exakta, S.A. de C.V. (Mexico)
  • Prost-Data, Inc. (United States)
  • Curna, Inc. (United States)
  • Modex Therapeutics, Inc. (United States)
  • Opko Instrumentation, LLC (United States)
  • Transition Therapeutics Inc (Canada)
  • Opko Ophthalmologics (United States)
  • OPKO BIOLOGICS LTD (Israel)

Data availability

Those 12 subsidiaries span United States, Mexico, Canada, Israel jurisdictions, though this list should not be read as complete — subsidiaries only become visible here where shareholder data has actually been filed with a register, so holdings in jurisdictions without that filing simply won't appear. Two of the 12 go a level deeper still, with their own further subsidiaries recorded beneath them — additional ownership layers this view doesn't expand.

Ultimate HQ
OPKO HEALTH, INC.
United States
Opko Diagnostics, LLC
United StatesUS FL 0450037401

Opko Pharmaceuticals, LLC
United StatesUS FL L13000165694

Pharmacos Exakta, S.A. de C.V.
MexicoMX PEX570708IM2

Prost-Data, Inc.
United StatesUS NJ 1900573603

Curna, Inc.
United StatesUS FL 4555915

Modex Therapeutics, Inc.
United StatesUS MA 3364718

Opko Instrumentation, LLC
United StatesUS FL 4371108

Transition Therapeutics Inc+ subsidiaries
Canada#0312497371

+4 more entities

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Map the complete corporate hierarchy: parent companies, subsidiaries, and cross-border ownership chains.

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Frequently Asked Questions

Who owns OPKO HEALTH, INC.?

Five shareholders are currently on record for OPKO HEALTH, INC., reflecting the stock ledger maintained under state corporate law (e.g. §219 of the Delaware General Corporation Law) rather than a public filing. The largest of these is iShares Trust-iShares Russell 2000 ETF, holding 5% — the largest recorded stake — followed by iShares Trust-iShares Russell 2000 ETF at 4.8%; the remaining 3 shareholders shown hold smaller stakes. Because every shareholder shown is a company rather than an individual, the ownership chain continues above this level, and no beneficial owner can be established from this filing alone.

Who is OPKO HEALTH, INC.'s UBO (Ultimate Beneficial Owner)?

Every shareholder recorded for OPKO HEALTH, INC. is itself a company rather than a natural person, so no Ultimate Beneficial Owner (UBO) is identified at this level; establishing one would require tracing the ownership of each shareholding company in turn.

How many shareholders does OPKO HEALTH, INC. have on record?

5 shareholders are shown on record for OPKO HEALTH, INC.. The register reports 7 in total; only the top 5 by holding are shown here.

What is OPKO HEALTH, INC.'s company registration number?

OPKO HEALTH, INC.'s registration number is F07000003863, filed with Florida Department of State — Sunbiz in United States. Its current status on the register is active.

Is OPKO HEALTH, INC. still an active company?

OPKO HEALTH, INC.'s status on Florida Department of State — Sunbiz is listed as active.

When was OPKO HEALTH, INC. incorporated?

OPKO HEALTH, INC. was incorporated on 31 July 2007, according to Florida Department of State — Sunbiz.

What is OPKO HEALTH, INC.'s registered address?

The registered address on file for OPKO HEALTH, INC. is Miami, United States.

Who are the officers/directors of OPKO HEALTH, INC.?

The Chairman & Ceo of OPKO HEALTH, INC. currently on record is Phillip Frost Ph.d.; 21 officers are currently on record for OPKO HEALTH, INC., filed with Florida Department of State — Sunbiz. Management authority at OPKO HEALTH, INC. sits with these individuals, not with shareholders, who are covered separately and hold ownership rather than control.

Does OPKO HEALTH, INC. have a parent company or subsidiaries?

OPKO HEALTH, INC. has no recorded parent company — it sits at the top of its own group structure, with 12 subsidiaries recorded beneath it across 4 jurisdictions. Those 12 subsidiaries span United States, Mexico, Canada, Israel jurisdictions, though this list should not be read as complete — subsidiaries only become visible here where shareholder data has actually been filed with a register, so holdings in jurisdictions without that filing simply won't appear. Two of the 12 go a level deeper still, with their own further subsidiaries recorded beneath them — additional ownership layers this view doesn't expand.

Can Zavia monitor changes to OPKO HEALTH, INC.'s ownership over time?

This profile reflects a point-in-time snapshot from Florida Department of State — Sunbiz. Zavia's monitoring API can track changes to OPKO HEALTH, INC.'s registered shareholders, officers, and group structure going forward, flagging updates as they're filed rather than requiring a manual recheck.

Can I access OPKO HEALTH, INC.'s data through an API?

Yes. Zavia's API connects directly to official government ownership registries across 195 countries and territories, including United States, so records like OPKO HEALTH, INC.'s registration, shareholder, UBO, and group-structure data can be queried programmatically instead of viewed one page at a time.

Where does this company information come from, and how current is it?

This record is sourced directly from Florida Department of State — Sunbiz and was last synced on 16 September 2026.

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