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VERTEX PHARMACEUTICALS INCORPORATED

Public Limited Company Active

in

VERTEX PHARMACEUTICALS INCORPORATED is a Public Limited Company registered in United States under 043039129, and its current status with Massachusetts Secretary of the Commonwealth is active. The company was incorporated on 4 January 1989 and lists its registered address as United States. 4 shareholders are on record for VERTEX PHARMACEUTICALS INCORPORATED, and since every one of them is a company rather than an individual, this particular filing does not on its own establish an ultimate beneficial owner (UBO) — identifying one would mean tracing the ownership of each shareholding company in turn. This profile is sourced directly from Massachusetts Secretary of the Commonwealth and was last updated on 25 September 2026.

From the registry

Registration details

Registration No.
043039129
Incorporation Date
1989-01-04
Company Type
Public Limited Company
Address
United States
Source: Massachusetts Secretary of the CommonwealthRegistry coverage

Shareholders

4

Shareholders of VERTEX PHARMACEUTICALS INCORPORATED

Four shareholders are currently on record for VERTEX PHARMACEUTICALS INCORPORATED, reflecting the stock ledger maintained under state corporate law (e.g. §219 of the Delaware General Corporation Law) rather than a public filing. The largest of these is Vanguard Group Inc, holding 12.7% — the largest recorded stake — followed by JPMORGAN CHASE & CO at 6.8%; the remaining 2 shareholders shown hold smaller stakes. Because every shareholder shown is a company rather than an individual, the ownership chain continues above this level, and no beneficial owner can be established from this filing alone.

Swipe or scroll for more columns

Shareholder Type Holding Source Document
Vanguard Group Inc 12.7% Massachusetts Secretary of the Commonwealth
JPMORGAN CHASE & CO 6.8% Massachusetts Secretary of the Commonwealth

Officers

32

Directors and officers of VERTEX PHARMACEUTICALS INCORPORATED

The Executive Chairman of VERTEX PHARMACEUTICALS INCORPORATED currently on record is Jeffrey Marc Leiden M.d., Ph.d.; 16 of the 32 officer records shown for VERTEX PHARMACEUTICALS INCORPORATED are current appointments, filed with Massachusetts Secretary of the Commonwealth. The remaining 15 records shown (Nancy Thornberry, Michel Lagarde and 13 others) are former appointments that have since been resigned. Management authority at VERTEX PHARMACEUTICALS INCORPORATED sits with these individuals, not with shareholders, who are covered separately and hold ownership rather than control. The source filing doesn't specify representation authority — whether officers can act individually or must sign jointly to bind the company — so that detail isn't available here.

JM
Jeffrey Marc Leiden M.d., Ph.d. ACTIVE

Residence
🇺🇸 United States
Occupation
Executive Chairman

RK
Reshma Kewalramani Fasn, M.d. ACTIVE

Residence
🇺🇸 United States
Occupation
Ceo, President & Director

RK
Reshma Kewalramani ACTIVE

Residence
🇺🇸 United States
Occupation
Director

DM
David M. Altshuler M.d., Ph.d. ACTIVE

Residence
🇺🇸 United States
Occupation
Executive Vp & Chief Scientific Officer

ND
NINA DEVLIN ACTIVE

Residence
🇺🇸 United States
Occupation
Senior Vp & Chief Communications Officer

SF
Stephanie Franklin ACTIVE

Residence
🇺🇸 United States
Occupation
Senior Vp & Chief Human Resources Officer

MT
Mike Tirozzi ACTIVE

Residence
🇺🇸 United States
Occupation
Svp And Chief Information & Data Officer

SA
Stuart A. Arbuckle B.sc. ACTIVE

Residence
🇺🇸 United States
Occupation
Executive Vp & Coo

CS
Corporation Service Company ACTIVE ENTITY

Residence
🇺🇸 United States
Occupation
Agent

OT
Ourania Tatsis Ph.d. ACTIVE

Residence
🇺🇸 United States
Occupation
Executive Vp And Chief Regulatory & Quality Officer

KC
Kristen C. Ambrose Cpa ACTIVE

Residence
🇺🇸 United States
Occupation
Senior Vp & Chief Accounting Officer

SL
Susie Lisa ACTIVE

Residence
🇺🇸 United States
Occupation
Senior Vice President Of Investor Relations

JB
Jonathan Biller J.d. ACTIVE

Residence
🇺🇸 United States
Occupation
Executive Vp & Chief Legal Officer

CF
Charles F. Wagner Jr. ACTIVE

Residence
🇺🇸 United States
Occupation
Executive Vp & Cfo

SL
Susie Lisa C.f.a. ACTIVE

Residence
🇺🇸 United States
Occupation
Senior Vice President Of Investor Relations

RK
Reshma Kewalramani ACTIVE

Residence
🇺🇸 United States
Occupation
President

RK
Reshma Kewalramani RESIGNED

Residence
🇺🇸 United States
Occupation
Ceo

NT
Nancy Thornberry RESIGNED

Residence
🇺🇸 United States
Occupation
Director

ML
Michel Lagarde RESIGNED

Residence
🇺🇸 United States
Occupation
Director

JL
Jeffrey Leiden RESIGNED

Residence
🇺🇸 United States
Occupation
Director

LC
Lloyd Carney RESIGNED

Residence
🇺🇸 United States
Occupation
Director

SB
Sangeeta Bhatia RESIGNED

Residence
🇺🇸 United States
Occupation
Director

BS
Bruce Sachs RESIGNED

Residence
🇺🇸 United States
Occupation
Director

AG
Alan Garber RESIGNED

Residence
🇺🇸 United States
Occupation
Director

JS
Jennifer Schneider RESIGNED

Residence
🇺🇸 United States
Occupation
Director

DM
Diana Mckenzie RESIGNED

Residence
🇺🇸 United States
Occupation
Director

SU
Suketu Upadhyay RESIGNED

Residence
🇺🇸 United States
Occupation
Director

CW
Charles Wagner Jr. RESIGNED

Residence
🇺🇸 United States
Occupation
Treasurer

KA
Kristen Ambrose RESIGNED

Residence
🇺🇸 United States
Occupation
Assistant Treasurer

PT
Prasanna Thombre RESIGNED

Residence
🇺🇸 United States
Occupation
Assistant Treasurer

OW
Omar White RESIGNED

Residence
🇺🇸 United States
Occupation
Assistant Secretary

JL
Joy Liu RESIGNED

Residence
🇺🇸 United States
Occupation
Secretary

Group Structure

Group structure of VERTEX PHARMACEUTICALS INCORPORATED

VERTEX PHARMACEUTICALS INCORPORATED has no recorded parent company — it sits at the top of its own group structure, with 21 subsidiaries recorded beneath it across 8 jurisdictions. Each of these downward relationships is derived rather than filed: resolved by matching entities across the registry network, not stated directly in a single document.

  • Alpine Immune Sciences, Inc. (United States)
  • VERTEX PHARMACEUTICALS (SPAIN) SL. (Spain)
  • VERTEX PHARMACEUTICALS (AUSTRALIA) PTY. LTD. (Australia)
  • Torreyana Insurance Company, Inc. (United States)
  • Vertex Pharmaceuticals (Netherlands) B.V. (Netherlands)
  • Exonics Therapeutics, Inc. (United States)
  • Semma Therapeutics, Inc. (United States)
  • Vertex Pharmaceuticals (Canada) Incorporated (Canada)
  • The Vertex Foundation Inc (United States)
  • Vertex Pharmaceuticals (Cayman) Limited (Cayman Islands)

Data availability

Those 21 subsidiaries span United States, Spain, Australia, Netherlands, Canada, Cayman Islands, and 2 more jurisdictions, though this list should not be read as complete — subsidiaries only become visible here where shareholder data has actually been filed with a register, so holdings in jurisdictions without that filing simply won't appear. Three of the 21 go a level deeper still, with their own further subsidiaries recorded beneath them — additional ownership layers this view doesn't expand.

Top of recorded group
VERTEX PHARMACEUTICALS INCORPORATED
United States
Alpine Immune Sciences, Inc.+ subsidiaries
United States#0132527538

VERTEX PHARMACEUTICALS (SPAIN) SL.
SpainES B86631686

VERTEX PHARMACEUTICALS (AUSTRALIA) PTY. LTD.
AustraliaAU 160157157

Torreyana Insurance Company, Inc.
United StatesUS VT 0338460

Vertex Pharmaceuticals (Netherlands) B.V.
NetherlandsNL 59126639

Exonics Therapeutics, Inc.
United StatesUS MA 6233154

Semma Therapeutics, Inc.
United StatesUS MA 5648205

Vertex Pharmaceuticals (Canada) Incorporated
CanadaCA 8387001

+13 more entities

Registry questions

Frequently asked questions

Who owns VERTEX PHARMACEUTICALS INCORPORATED?

Four shareholders are currently on record for VERTEX PHARMACEUTICALS INCORPORATED, reflecting the stock ledger maintained under state corporate law (e.g. §219 of the Delaware General Corporation Law) rather than a public filing. The largest of these is Vanguard Group Inc, holding 12.7% — the largest recorded stake — followed by JPMORGAN CHASE & CO at 6.8%; the remaining 2 shareholders shown hold smaller stakes. Because every shareholder shown is a company rather than an individual, the ownership chain continues above this level, and no beneficial owner can be established from this filing alone.

Who is VERTEX PHARMACEUTICALS INCORPORATED's UBO (Ultimate Beneficial Owner)?

Every shareholder recorded for VERTEX PHARMACEUTICALS INCORPORATED is itself a company rather than a natural person, so no Ultimate Beneficial Owner (UBO) is identified at this level; establishing one would require tracing the ownership of each shareholding company in turn.

How many shareholders does VERTEX PHARMACEUTICALS INCORPORATED have on record?

4 shareholders are shown on record for VERTEX PHARMACEUTICALS INCORPORATED.

What is VERTEX PHARMACEUTICALS INCORPORATED's company registration number?

VERTEX PHARMACEUTICALS INCORPORATED's registration number is 043039129, filed with Massachusetts Secretary of the Commonwealth in United States. Its current status on the register is active.

Is VERTEX PHARMACEUTICALS INCORPORATED still an active company?

VERTEX PHARMACEUTICALS INCORPORATED's status on Massachusetts Secretary of the Commonwealth is listed as active.

When was VERTEX PHARMACEUTICALS INCORPORATED incorporated?

VERTEX PHARMACEUTICALS INCORPORATED was incorporated on 4 January 1989, according to Massachusetts Secretary of the Commonwealth.

What is VERTEX PHARMACEUTICALS INCORPORATED's registered address?

The registered address on file for VERTEX PHARMACEUTICALS INCORPORATED is United States.

What legal structure is VERTEX PHARMACEUTICALS INCORPORATED registered as?

VERTEX PHARMACEUTICALS INCORPORATED is registered as a Public Limited Company in United States.

Who are the officers/directors of VERTEX PHARMACEUTICALS INCORPORATED?

The Executive Chairman of VERTEX PHARMACEUTICALS INCORPORATED currently on record is Jeffrey Marc Leiden M.d., Ph.d.; 16 of the 32 officer records shown for VERTEX PHARMACEUTICALS INCORPORATED are current appointments, filed with Massachusetts Secretary of the Commonwealth. The remaining 15 records shown (Nancy Thornberry, Michel Lagarde and 13 others) are former appointments that have since been resigned. Management authority at VERTEX PHARMACEUTICALS INCORPORATED sits with these individuals, not with shareholders, who are covered separately and hold ownership rather than control.

Does VERTEX PHARMACEUTICALS INCORPORATED have a parent company or subsidiaries?

VERTEX PHARMACEUTICALS INCORPORATED has no recorded parent company — it sits at the top of its own group structure, with 21 subsidiaries recorded beneath it across 8 jurisdictions. Those 21 subsidiaries span United States, Spain, Australia, Netherlands, Canada, Cayman Islands, and 2 more jurisdictions, though this list should not be read as complete — subsidiaries only become visible here where shareholder data has actually been filed with a register, so holdings in jurisdictions without that filing simply won't appear. Three of the 21 go a level deeper still, with their own further subsidiaries recorded beneath them — additional ownership layers this view doesn't expand.

Can Zavia monitor changes to VERTEX PHARMACEUTICALS INCORPORATED's ownership over time?

This profile reflects a point-in-time snapshot from Massachusetts Secretary of the Commonwealth. Zavia's monitoring API can track changes to VERTEX PHARMACEUTICALS INCORPORATED's registered shareholders, officers, and group structure going forward, flagging updates as they're filed rather than requiring a manual recheck.

Can I access VERTEX PHARMACEUTICALS INCORPORATED's data through an API?

Yes. Zavia's API connects directly to official government ownership registries across 195 countries and territories, including United States, so records like VERTEX PHARMACEUTICALS INCORPORATED's registration, shareholder, UBO, and group-structure data can be queried programmatically instead of viewed one page at a time.

Where does this company information come from, and how current is it?

This record is sourced directly from Massachusetts Secretary of the Commonwealth and was last synced on 25 September 2026.

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