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IONIS PHARMACEUTICALS, INC.

Active

in

Registration No.
1684168
Incorporation Date
1991-04-02
Company Type
Not disclosed
Address
United States
Website
www.ionispharma.com/
Source: California Secretary of State — bizfile Online

IONIS PHARMACEUTICALS, INC. is a registered legal entity registered in United States under 1684168, and its current status with California Secretary of State — bizfile Online is active. The company was incorporated on 2 April 1991 and lists its registered address as United States. 5 shareholders are on record for IONIS PHARMACEUTICALS, INC., and since every one of them is a company rather than an individual, this particular filing does not on its own establish an ultimate beneficial owner (UBO) — identifying one would mean tracing the ownership of each shareholding company in turn. This profile is sourced directly from California Secretary of State — bizfile Online and was last updated on 22 September 2026.

Data Provenance
This record is sourced directly from official government registries, including California Secretary of State — bizfile Online.

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Shareholders

5

Shareholders of IONIS PHARMACEUTICALS, INC.

Five shareholders are currently on record for IONIS PHARMACEUTICALS, INC., reflecting the stock ledger maintained under state corporate law (e.g. §219 of the Delaware General Corporation Law) rather than a public filing. The largest of these is Vanguard Group Inc, holding 11.3% — the largest recorded stake — followed by Fidelity Mt. Vernon Street Trust-Fidelity Growth Company Fund at 5.6%; the remaining 3 shareholders shown hold smaller stakes. Because every shareholder shown is a company rather than an individual, the ownership chain continues above this level, and no beneficial owner can be established from this filing alone.

Shareholder Type Holding Source Document
Vanguard Group Inc 11.3% California Secretary of State — bizfile Online
Fidelity Mt. Vernon Street Trust-Fidelity Growth Company Fund 5.6% California Secretary of State — bizfile Online
GROWTH FUND OF AMERICA 4.4% California Secretary of State — bizfile Online
NEW ECONOMY FUND 2.7% California Secretary of State — bizfile Online
Fidelity Mt. Vernon Street Trust-Fidelity Growth Company K6 Fund 1.6% California Secretary of State — bizfile Online

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Full cap table, ownership percentages, and ultimate beneficial owners resolved down to the natural person.

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Officers

5

Directors and officers of IONIS PHARMACEUTICALS, INC.

The Director of IONIS PHARMACEUTICALS, INC. currently on record is PETER REIKES; five officers are currently on record for IONIS PHARMACEUTICALS, INC., filed with California Secretary of State — bizfile Online. Management authority at IONIS PHARMACEUTICALS, INC. sits with these individuals, not with shareholders, who are covered separately and hold ownership rather than control. The source filing doesn't specify representation authority — whether officers can act individually or must sign jointly to bind the company — so that detail isn't available here.

Data availability

The register reports 28 officers in total, including past appointments, though only the 5 most relevant records are shown here.

PR
PETER REIKES ACTIVE

Residence
🇺🇸 United States
Occupation
Director

MH
MICHAEL HAYDEN ACTIVE

Residence
🇺🇸 United States
Occupation
Director

CF
C. Frank Bennett Bsc, Ph.d. ACTIVE

Residence
🇺🇸 United States
Occupation
Executive Vp & Chief Scientific Officer

EE
Eric E. Swayze Ph.d. ACTIVE

Residence
🇺🇸 United States
Occupation
Executive Vice President Of Research

TB
Tracy Berns J.d. ACTIVE

Residence
🇺🇸 United States
Occupation
Senior Vp And Chief Compliance & Quality Assurance Officer

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Group Structure

Group structure of IONIS PHARMACEUTICALS, INC.

IONIS PHARMACEUTICALS, INC. has no recorded parent company — it sits at the top of its own group structure, with 12 subsidiaries recorded beneath it across 3 jurisdictions. Each of these downward relationships is derived rather than filed: resolved by matching entities across the registry network, not stated directly in a single document.

  • Symphony Genisis, Inc., A Delaware Corporation (United States)
  • Osprey Therapeutics, Inc. (United States)
  • Perisis I Development Corporation, A Delaware Corporation (United States)
  • Osprey Therapeutics, Inc., A Delaware Corporation (United States)
  • IONIS DEVELOPMENT (IRELAND) LIMITED (Ireland)
  • Akcea Securities Corporation. (United States)
  • Akcea Therapeutics, Inc. (United States)
  • Symphony Genisis, Inc. (United States)
  • IONIS USA LIMITED (United Kingdom)
  • Ionis Gazelle, LLC (United States)

Data availability

Those 12 subsidiaries span United States, Ireland, United Kingdom jurisdictions, though this list should not be read as complete — subsidiaries only become visible here where shareholder data has actually been filed with a register, so holdings in jurisdictions without that filing simply won't appear. One of the 12 go a level deeper still, with its own further subsidiaries recorded beneath it — additional ownership layers this view doesn't expand.

Ultimate HQ
IONIS PHARMACEUTICALS, INC.
United States
Symphony Genisis, Inc., A Delaware Corporation
United States#0229477972

Osprey Therapeutics, Inc.
United StatesUS CA 6673858

Perisis I Development Corporation, A Delaware Corporation
United States#0229475697

Osprey Therapeutics, Inc., A Delaware Corporation
United States#0229475295

IONIS DEVELOPMENT (IRELAND) LIMITED
IrelandIE 643143

Akcea Securities Corporation.
United States#0228376520

Akcea Therapeutics, Inc.+ subsidiaries
United StatesUS CA 5644939

Symphony Genisis, Inc.
United States#0911347944

+4 more entities

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Frequently Asked Questions

Who owns IONIS PHARMACEUTICALS, INC.?

Five shareholders are currently on record for IONIS PHARMACEUTICALS, INC., reflecting the stock ledger maintained under state corporate law (e.g. §219 of the Delaware General Corporation Law) rather than a public filing. The largest of these is Vanguard Group Inc, holding 11.3% — the largest recorded stake — followed by Fidelity Mt. Vernon Street Trust-Fidelity Growth Company Fund at 5.6%; the remaining 3 shareholders shown hold smaller stakes. Because every shareholder shown is a company rather than an individual, the ownership chain continues above this level, and no beneficial owner can be established from this filing alone.

Who is IONIS PHARMACEUTICALS, INC.'s UBO (Ultimate Beneficial Owner)?

Every shareholder recorded for IONIS PHARMACEUTICALS, INC. is itself a company rather than a natural person, so no Ultimate Beneficial Owner (UBO) is identified at this level; establishing one would require tracing the ownership of each shareholding company in turn.

How many shareholders does IONIS PHARMACEUTICALS, INC. have on record?

5 shareholders are shown on record for IONIS PHARMACEUTICALS, INC..

What is IONIS PHARMACEUTICALS, INC.'s company registration number?

IONIS PHARMACEUTICALS, INC.'s registration number is 1684168, filed with California Secretary of State — bizfile Online in United States. Its current status on the register is active.

Is IONIS PHARMACEUTICALS, INC. still an active company?

IONIS PHARMACEUTICALS, INC.'s status on California Secretary of State — bizfile Online is listed as active.

When was IONIS PHARMACEUTICALS, INC. incorporated?

IONIS PHARMACEUTICALS, INC. was incorporated on 2 April 1991, according to California Secretary of State — bizfile Online.

What is IONIS PHARMACEUTICALS, INC.'s registered address?

The registered address on file for IONIS PHARMACEUTICALS, INC. is United States.

Who are the officers/directors of IONIS PHARMACEUTICALS, INC.?

The Director of IONIS PHARMACEUTICALS, INC. currently on record is PETER REIKES; five officers are currently on record for IONIS PHARMACEUTICALS, INC., filed with California Secretary of State — bizfile Online. Management authority at IONIS PHARMACEUTICALS, INC. sits with these individuals, not with shareholders, who are covered separately and hold ownership rather than control.

Does IONIS PHARMACEUTICALS, INC. have a parent company or subsidiaries?

IONIS PHARMACEUTICALS, INC. has no recorded parent company — it sits at the top of its own group structure, with 12 subsidiaries recorded beneath it across 3 jurisdictions. Those 12 subsidiaries span United States, Ireland, United Kingdom jurisdictions, though this list should not be read as complete — subsidiaries only become visible here where shareholder data has actually been filed with a register, so holdings in jurisdictions without that filing simply won't appear. One of the 12 go a level deeper still, with its own further subsidiaries recorded beneath it — additional ownership layers this view doesn't expand.

Can Zavia monitor changes to IONIS PHARMACEUTICALS, INC.'s ownership over time?

This profile reflects a point-in-time snapshot from California Secretary of State — bizfile Online. Zavia's monitoring API can track changes to IONIS PHARMACEUTICALS, INC.'s registered shareholders, officers, and group structure going forward, flagging updates as they're filed rather than requiring a manual recheck.

Can I access IONIS PHARMACEUTICALS, INC.'s data through an API?

Yes. Zavia's API connects directly to official government ownership registries across 195 countries and territories, including United States, so records like IONIS PHARMACEUTICALS, INC.'s registration, shareholder, UBO, and group-structure data can be queried programmatically instead of viewed one page at a time.

Where does this company information come from, and how current is it?

This record is sourced directly from California Secretary of State — bizfile Online and was last synced on 22 September 2026.

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