SPYRE THERAPEUTICS, INC.
SPYRE THERAPEUTICS, INC. is a Public Limited Company registered in United States under 001678967, and its current status with Massachusetts Secretary of the Commonwealth is active. The company was incorporated on 24 July 2023 and lists its registered address as United States. 3 shareholders are on record for SPYRE THERAPEUTICS, INC., and since every one of them is a company rather than an individual, this particular filing does not on its own establish an ultimate beneficial owner (UBO) — identifying one would mean tracing the ownership of each shareholding company in turn. This profile is sourced directly from Massachusetts Secretary of the Commonwealth and was last updated on 4 October 2026.
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Shareholders
3
Three shareholders are currently on record for SPYRE THERAPEUTICS, INC., reflecting the stock ledger maintained under state corporate law (e.g. §219 of the Delaware General Corporation Law) rather than a public filing.
The largest of these is Vanguard Group Inc, holding 7.8% — the largest recorded stake — followed by SmallCap World Fund Inc at 7.2%; the remaining 1 shareholder shown holds smaller stakes.
Because every shareholder shown is a company rather than an individual, the ownership chain continues above this level, and no beneficial owner can be established from this filing alone.
| Shareholder | Type | Holding | Source Document |
|---|---|---|---|
| Vanguard Group Inc | 7.8% | Massachusetts Secretary of the Commonwealth | |
| SmallCap World Fund Inc | 7.2% | Massachusetts Secretary of the Commonwealth | |
| Braidwell LP | 5% | Massachusetts Secretary of the Commonwealth |
Officers
5
The Ceo & Director of SPYRE THERAPEUTICS, INC. currently on record is Cameron Turtle Dphil, Ph.d.; five officers are currently on record for SPYRE THERAPEUTICS, INC., filed with Massachusetts Secretary of the Commonwealth.
The register reports 36 officers in total, including past appointments, though only the 5 most relevant records are shown here.
Management authority at SPYRE THERAPEUTICS, INC. sits with these individuals, not with shareholders, who are covered separately and hold ownership rather than control.
The source filing doesn't specify representation authority — whether officers can act individually or must sign jointly to bind the company — so that detail isn't available here.
Group Structure
SPYRE THERAPEUTICS, INC. has no recorded parent company — it sits at the top of its own group structure, with 8 subsidiaries recorded beneath it across 1 jurisdiction. Each of these downward relationships is derived rather than filed: resolved by matching entities across the registry network, not stated directly in a single document.
Those 8 subsidiaries span United States jurisdiction, though this list should not be read as complete — subsidiaries only become visible here where shareholder data has actually been filed with a register, so holdings in jurisdictions without that filing simply won't appear.
SPYRE THERAPEUTICS, INC.
United States
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Frequently Asked Questions
Who owns SPYRE THERAPEUTICS, INC.?
Three shareholders are currently on record for SPYRE THERAPEUTICS, INC., reflecting the stock ledger maintained under state corporate law (e.g. §219 of the Delaware General Corporation Law) rather than a public filing. The largest of these is Vanguard Group Inc, holding 7.8% — the largest recorded stake — followed by SmallCap World Fund Inc at 7.2%; the remaining 1 shareholder shown holds smaller stakes. Because every shareholder shown is a company rather than an individual, the ownership chain continues above this level, and no beneficial owner can be established from this filing alone.
Who is SPYRE THERAPEUTICS, INC.'s UBO (Ultimate Beneficial Owner)?
Every shareholder recorded for SPYRE THERAPEUTICS, INC. is itself a company rather than a natural person, so no Ultimate Beneficial Owner (UBO) is identified at this level; establishing one would require tracing the ownership of each shareholding company in turn.
How many shareholders does SPYRE THERAPEUTICS, INC. have on record?
3 shareholders are shown on record for SPYRE THERAPEUTICS, INC..
What is SPYRE THERAPEUTICS, INC.'s company registration number?
SPYRE THERAPEUTICS, INC.'s registration number is 001678967, filed with Massachusetts Secretary of the Commonwealth in United States. Its current status on the register is active.
Is SPYRE THERAPEUTICS, INC. still an active company?
SPYRE THERAPEUTICS, INC.'s status on Massachusetts Secretary of the Commonwealth is listed as active.
When was SPYRE THERAPEUTICS, INC. incorporated?
SPYRE THERAPEUTICS, INC. was incorporated on 24 July 2023, according to Massachusetts Secretary of the Commonwealth.
What is SPYRE THERAPEUTICS, INC.'s registered address?
The registered address on file for SPYRE THERAPEUTICS, INC. is United States.
What legal structure is SPYRE THERAPEUTICS, INC. registered as?
SPYRE THERAPEUTICS, INC. is registered as a Public Limited Company in United States.
Who are the officers/directors of SPYRE THERAPEUTICS, INC.?
The Ceo & Director of SPYRE THERAPEUTICS, INC. currently on record is Cameron Turtle Dphil, Ph.d.; five officers are currently on record for SPYRE THERAPEUTICS, INC., filed with Massachusetts Secretary of the Commonwealth. Management authority at SPYRE THERAPEUTICS, INC. sits with these individuals, not with shareholders, who are covered separately and hold ownership rather than control.
Does SPYRE THERAPEUTICS, INC. have a parent company or subsidiaries?
SPYRE THERAPEUTICS, INC. has no recorded parent company — it sits at the top of its own group structure, with 8 subsidiaries recorded beneath it across 1 jurisdiction. Those 8 subsidiaries span United States jurisdiction, though this list should not be read as complete — subsidiaries only become visible here where shareholder data has actually been filed with a register, so holdings in jurisdictions without that filing simply won't appear.
Can Zavia monitor changes to SPYRE THERAPEUTICS, INC.'s ownership over time?
This profile reflects a point-in-time snapshot from Massachusetts Secretary of the Commonwealth. Zavia's monitoring API can track changes to SPYRE THERAPEUTICS, INC.'s registered shareholders, officers, and group structure going forward, flagging updates as they're filed rather than requiring a manual recheck.
Can I access SPYRE THERAPEUTICS, INC.'s data through an API?
Yes. Zavia's API connects directly to official government ownership registries across 195 countries and territories, including United States, so records like SPYRE THERAPEUTICS, INC.'s registration, shareholder, UBO, and group-structure data can be queried programmatically instead of viewed one page at a time.
Where does this company information come from, and how current is it?
This record is sourced directly from Massachusetts Secretary of the Commonwealth and was last synced on 4 October 2026.